That doesn't look like a menu from Final Cut? Or least I never seen it inside FCP
Sorry just saw that this is a Compressor question.. Will never get used to this forum setup
As for an answer not sure as I don't use Compressor enough to come across this setting, guess best to just run a test and see if it makes a difference? I always think highest quality settings are best but might take too long for a real world scenario where you have to deliver on time. So the best setting that doesn't cause problems and therefor will be the most time efficient is what I would aim for.